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> Abstract: Practitioners from around the country …

John Kron

It’s the bane of doctors’ lives, but is there a legitimate place for red tape?

IT was an anxious wait for Dr Warwick Carter. He received a phone call from the PBS saying his prescribing profile was ‘grossly abnormal’ and he was to receive a visit from a PBS official the following week.

In the ensuing days Dr Carter, a GP in Sumner Park, Queensland, racked his worried mind trying to identify what was abnormal about his prescrib…

Baclofen, a derivative of [gamma]-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity, particularly in patients with multiple sclerosis. (1) Although its exact mechanism is not fully understood, its main effects at the spinal end of upper motor neurons are thought to cause muscle relaxation. Adverse effects of baclofen a…

AGI announces key findings of clinical PK study of arbaclofen (AGI-006)

Dublin, Ireland, 2 April 2008 - AGI Therapeutics plc (”AGI” or the “Company”)
(AIM, IEX: AGI), a speciality pharmaceutical company focused on gastrointestinal
drug products, today announces the key…

Purpose: Multiple deformations of the lower limbs are common orthopaedic complications of central nervous system disease. Assessment is difficult. Intrathecal Lioresal was proposed for the patients to establish the relative effects of spasticity and musculo-tendi…

ABSTRACT
Intrathecal baclofen (ITB) is a relatively new treatment approach that may be useful for treating spasticity in patients with chronic stroke. In this paper, we examine ITB treatment of spastieity caused by stroke and the implications for physical therapy man…

Tokyo, Apr 5, 2006 - (JCN) - Some of Daiichi Pharmaceutical’s Intrathecal Baclofen therapy products are now listed for national health insurance reimbursement. One of them is the SynchroMed infusion system that comprises of the SynchroMed EL pump and the InDura catheter.
Intrathecal Gabalon (baclofen) and the SynchroMed system are used to treat severe spasticity in patients if conventional treatments don’t. The system i…

ATLANTA — Baclofen inhibits transient lower esophageal sphincter relaxations associated with duodenogastroesophageal reflux, Dr. Geert Koek said at the annual Digestive Disease Week.
According to Dr. Geert Koek of Catholic University, Leuven, Belgium, duodenogastroesophageal reflux disease is differentiated from gastroesophageal reflux disease by significant amounts of refluxed bile from the duodenum. Patients can have persist…

New Dosage Expands Sales Reach
PHILADELPHIA — Lannett Company, Inc. (AMEX:LCI), a manufacturer of generic pharmaceuticals, today announced that it has received approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Baclofen 10mg tablets, bolstering the company’s existing product offering of Baclofen 20mg tablets.
Total U.S. annual sales as of May 2007 for Baclofen 10mg were $153 million and $108 million for Baclofen 20mg, accordin…

Health service purchasers are often faced with the problem of making decisions in the absence of evidence on benefit and cost. Evidence is most often lacking in rare but severe conditions, and in early applications of new technology. The example of intrathecal baclofen for severe spasticity [1] shows that even in these difficult circumstances sufficient evidence may be garnered…