Archive for November, 2008

Business Wire - Tight, Stiff Muscles of Stroke Survivors Improved After Receiving Baclofen Through Implanted Pump

Friday, November 28th, 2008

Business Editors & Health Writers
MINNEAPOLIS–(BUSINESS WIRE)–Oct. 16, 2001
UAB researchers found that Medtronic’s ITB(TM)
Therapy helped to free patients’ locked’ limbs
Results of…

News: FDA Classifies Medtronic's Notification Related to Improper …

Wednesday, November 26th, 2008

Medtronic, Inc. (NYSE:MDT) today announced that the U.S. Food and
Drug Administration (FDA) has classified its safety alert about the
proper connection of sutureless catheters used with implantable drug
infusion systems as a Class I recall. The notification relates to the
improper connection of its sutureless connector intrathecal catheters
(referred to as SC catheters). The affected products include th…

News: XenoPort to Expand Clinical Development of XP19986. Genetic …

Saturday, November 22nd, 2008

XenoPort, Inc. (Nasdaq:XNPT) announced plans to initiate an
exploratory Phase 2 clinical trial of XP19986 in patients with acute
back spasms, which is a debilitating condition affecting approximately
two-thirds of patients experiencing lower back pain. XenoPort intends
to initiate this two-week, multi-center, double-blind, place…

Journal of Neuroscience Nursing - Intrathecal baclofen therapy: ten steps toward best practice.

Wednesday, November 19th, 2008

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Australian Doctor - Balancing act.(general practice regulations)

Thursday, November 13th, 2008

John Kron

It’s the bane of doctors’ lives, but is there a legitimate place for red tape?

IT was an anxious wait for Dr Warwick Carter. He received a phone call from the PBS saying his prescribing profile was ‘grossly abnormal’ and he was to receive a visit from a PBS official the following week.

In the ensuing days Dr Carter, a GP in Sumner Park, Queensland, racked his worried mind trying to identify what was abnormal about his prescrib…

American Journal of Critical Care - An initially unsuspected case of baclofen overdose

Sunday, November 9th, 2008

Baclofen, a derivative of [gamma]-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity, particularly in patients with multiple sclerosis. (1) Although its exact mechanism is not fully understood, its main effects at the spinal end of upper motor neurons are thought to cause muscle relaxation. Adverse effects of baclofen a…

Market Wire - AGI Therapeutics plc announces key findings of clinical PK study of arbaclofen (AGI-006)

Friday, November 7th, 2008

AGI announces key findings of clinical PK study of arbaclofen (AGI-006)

Dublin, Ireland, 2 April 2008 - AGI Therapeutics plc (”AGI” or the “Company”)
(AIM, IEX: AGI), a speciality pharmaceutical company focused on gastrointestinal
drug products, today announces the key…

Journal of Bone and Joint Surgery - PLACE OF INTRATHECAL BACLOFEN TEST FOR ASSESSING NEURO-ORTHOPAEDIC COMPLICATIONS INVOLVING RETRACTION OF THE LOWER LIMBS

Tuesday, November 4th, 2008

Purpose: Multiple deformations of the lower limbs are common orthopaedic complications of central nervous system disease. Assessment is difficult. Intrathecal Lioresal was proposed for the patients to establish the relative effects of spasticity and musculo-tendi…

Journal of Neurologic Physical Therapy - Intrathecal Baclofen: A New Treatment Approach for Severe Spasticity in Patients with Stroke

Sunday, November 2nd, 2008

ABSTRACT
Intrathecal baclofen (ITB) is a relatively new treatment approach that may be useful for treating spasticity in patients with chronic stroke. In this paper, we examine ITB treatment of spastieity caused by stroke and the implications for physical therapy man…