American Journal of Critical Care - An initially unsuspected case of baclofen overdose
Sunday, November 9th, 2008Baclofen, a derivative of [gamma]-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity, particularly in patients with multiple sclerosis. (1) Although its exact mechanism is not fully understood, its main effects at the spinal end of upper motor neurons are thought to cause muscle relaxation. Adverse effects of baclofen a…
