Internal Medicine News - Baclofen Reduces Symptoms of Duodenogastroesophageal Reflux.
ATLANTA — Baclofen inhibits transient lower esophageal sphincter relaxations associated with duodenogastroesophageal reflux, Dr. Geert Koek said at the annual Digestive Disease Week.
According to Dr. Geert Koek of Catholic University, Leuven, Belgium, duodenogastroesophageal reflux disease is differentiated from gastroesophageal reflux disease by significant amounts of refluxed bile from the duodenum. Patients can have persistent symptoms and lesions despite high doses of proton pump inhibitor (PPI) therapy
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Dr. Koek and his colleagues decided to treat patients with PPI therapy …
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